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Maternal Age Specific Odds of Fetal Down's Syndrome During the 2nd Trimester Based on Non-Structural Findings

 

Maternal Age

Pre-US Odds

Normal US Scan

Inc. Nuchal Thickness

Echogenic Bowel

Short Humerus

Short Femur

Echogenic Intracardiac Focus

Renal Pyelectasis

(Years)

(1:_)

(1:_)

(1:_)

(1:_)

(1:_)

(1:_)

(1:_)

(1:_)

20

1176

1960

63

214

511

470

588

735

21

1160

1933

62

211

504

464

580

725

22

1136

1893

61

207

494

454

568

710

23

1114

1857

60

203

484

446

557

696

24

1087

1812

58

198

473

435

544

679

25

1040

1733

56

189

452

416

520

650

26

990

1650

53

180

430

396

495

619

27

928

1547

50

169

403

371

464

580

28

855

1425

46

155

372

342

428

534

29

760

1267

41

138

330

304

380

475

30

690

1150

37

125

300

276

345

431

31

597

995

32

109

260

239

299

373

32

508

847

27

92

221

203

254

318

33

421

702

23

77

183

168

211

263

34

342

570

18

62

149

137

171

214

35

274

457

15

50

119

110

137

171

36

216

360

12

39

94

86

108

135

37

168

280

9

31

73

67

84

105

38

129

215

7

23

56

52

65

81

39

98

163

5

18

43

39

49

61

40

74

123

4

13

32

30

37

46

41

56

93

3

10

24

22

28

35

42

42

70

2

8

18

17

21

26

43

31

52

2

6

13

12

16

19

44

23

38

1

4

10

9

12

14

From: Nyberg DA, Luthy DA, Resta RG, Nyberg BC, Williams MA. Age-adjusted ultrasound risk assessment for fetal Down's syndrome during the second trimester: description of the method and analysis of 142 cases. Ultrasound Obstet Gynecol 12:8-14, 1998.

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Ultrasound Educational Press     Go Top
Peter W. Callen, M.D.
Professor of Radiology, Obstetrics, Gynecology and Reproductive Science
University of California Medical Center, San Francisco, California

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