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Normal Ranges for Nasal Bone Lengths

(in millimeters) n=3537

Sonek JD et al

 

Week
2.5th
5th
50th
95th
97.5th
Number
11
1.3
1.4
2.3
3.3
3.4
16
12
1.7
1.8
2.8
4.2
4.3
54
13
2.2
2.3
3.1
4.6
4.8
59
14
2.2
2.5
3.8
5.3
5.7
82
15
2.8
3.0
4.3
5.7
6.0
103
16
3.2
3.4
4.7
6.2
6.2
134
17
3.7
4.0
5.3
6.6
6.9
203
18
4.0
4.3
5.7
7.0
7.3
252
19
4.6
5.0
6.3
7.9
8.2
388
20
5.0
5.2
6.7
8.3
8.6
440
21
5.1
5.6
7.1
9.0
9.3
322
22
5.6
5.8
7.5
9.3
10.2
208
23
6.0
6.4
7.9
9.6
9.9
157
24
6.6
6.8
8.3
10.0
10.3
121
25
6.3
6.5
8.5
10.7
10.8
123
26
6.8
7.4
8.9
10.9
11.3
96
27
7.0
7.5
9.2
11.3
11.6
80
28
7.2
7.6
9.8
12.1
13.4
103
29
7.2
7.7
9.8
11.8
12.3
95
30
7.3
7.9
10.0
12.6
13.2
104
31
7.9
8.2
10.4
12.6
13.2
92
32
8.1
8.6
10.5
13.6
13.7
66
33
8.6
8.7
10.8
12.8
13.0
54
34
9.0
9.1
10.9
12.8
13.5
41
35
7.5
8.5
11.0
14.1
15.0
37
36
7.3
7.8
10.8
12.8
13.6
40
37
8.4
8.7
11.4
14.5
15.0
36
38
9.2
9.3
11.7
15.7
16.6
13
39
9.1
9.2
10.9
14.0
14.8
12
40
10.3
10.4
12.1
14.5
14.7
6

Sonek JD, McKenna D, Webb D, Croom C, Nicolaides K Nasal bone length throughout gestation: normal ranges based on 3537 fetal ultrasound measurements. Ultrasound Obstet Gynec 21:152-155, 2003

 

Nasal Bone Length Measurement

(millimeters)

Bunduki V et al

 

Gestational Age (weeks)
2.5th %
5th %
50th %
16 - 16+6
3.7
4.1
5.9
17 - 17+6
4.0
4.3
6.2
18 - 18+6
4.3
4.6
6.5
19 - 19+6
4.5
4.9
6.8
20 - 20+6
4.8
5.2
7.0
21 - 20+6
5.1
5.4
7.3
22 - 22+6
5.4
5.7
7.6
23 - 23+6
5.6
6.0
7.8
24
5.8
6.1
8.0

Bunduki V, Ruano R, Miguelez J et al. Fetal nasal bone length: reference range and clinical application in ultrasound screening for trisomy 21. Ultrasound Obstet Gynec 21:156-160, 2003

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Peter W. Callen, M.D.
Professor of Radiology, Obstetrics, Gynecology and Reproductive Science
University of California Medical Center, San Francisco, California
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